Choline's phosphorylation in rat striatal slices is regulated by the activity of cholinergic neurons.

@article{Farber1996CholinesPI,
  title={Choline's phosphorylation in rat striatal slices is regulated by the activity of cholinergic neurons.},
  author={Stephen A Farber and Vahide Savci and Andreas Wei and Barbara E. Slack and Richard J. Wurtman},
  journal={Brain research},
  year={1996},
  volume={723 1-2},
  pages={90-9}
}
The mechanism by which populations of brain cells regulate the flux of choline (Ch) into membrane or neurotransmitter biosynthesis was investigated using electrically stimulated superfused slices of rat corpus striatum. [Me-14C]Ch placed in the superfusion medium for 30 min during a 1-h stimulation period was incorporated into tissue [14C] phosphorylcholine (PCh) and [14C]phosphatidylcholine (PtdCh). Stimulation also caused a profound inhibition of PCh synthesis and a 10-fold increase in [14C… CONTINUE READING