Cholesterol of myelin is the determinant of gray-white contrast in MRI of brain.

@article{Koenig1991CholesterolOM,
  title={Cholesterol of myelin is the determinant of gray-white contrast in MRI of brain.},
  author={Seymour H. Koenig},
  journal={Magnetic resonance in medicine},
  year={1991},
  volume={20 2},
  pages={285-91}
}
The relative brightness of adult white matter in T1-weighted MRI arises from myelin, but the mechanisms responsible remain to be clarified. Koenig et al. [Magn. Reson. Med. 14, 482 (1990)] conjectured that the cholesterol of myelin (approximately 30% of its lipid) was responsible. We present 1/T1 and magnetization transfer contrast imaging data [Wolff and Balaban, Magn. Reson. Med. 10, 135 (1989)] on a model system--50% lipid--50% water by weight, with the lipid one-half phosphatidyl choline… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 76 extracted citations

Gray/White Matter Contrast in Parkinson’s Disease

Front. Aging Neurosci. • 2018
View 1 Excerpt

Networks of myelin covariance

Human brain mapping • 2018
View 1 Excerpt

Similar Papers

Loading similar papers…