Cholesterol modulates the dimer interface of the β₂-adrenergic receptor via cholesterol occupancy sites.

Abstract

The β2-adrenergic receptor is an important member of the G-protein-coupled receptor (GPCR) superfamily, whose stability and function are modulated by membrane cholesterol. The recent high-resolution crystal structure of the β2-adrenergic receptor revealed the presence of possible cholesterol-binding sites in the receptor. However, the functional relevance… (More)
DOI: 10.1016/j.bpj.2014.02.002

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Cite this paper

@article{Prasanna2014CholesterolMT, title={Cholesterol modulates the dimer interface of the β₂-adrenergic receptor via cholesterol occupancy sites.}, author={Xavier Prasanna and Amitabha Chattopadhyay and Durba Sengupta}, journal={Biophysical journal}, year={2014}, volume={106 6}, pages={1290-300} }