Cholesterol modulates activity of calcium-dependent ATPase of the sarcoplasmic reticulum

@article{Madden1979CholesterolMA,
  title={Cholesterol modulates activity of calcium-dependent ATPase of the sarcoplasmic reticulum},
  author={Thomas D. Madden and Peter J. Quinn and Dennis Chapman},
  journal={Nature},
  year={1979},
  volume={279},
  pages={538-541}
}
BIOMEMBRANES consist of an asymmetric lipid bilayer matrix into which and around which the various proteins are situated. The proteins may be attached to the outside of the lipid bilayer (extrinsic proteins), but in many cases the proteins (intrinsic proteins) are embedded within, and can span, the bilayer. Associated with this is the idea that in many cases the lipid matrix is in a fluid condition in which the lipids are essentially above their transition temperature (Tc) and able to diffuse… CONTINUE READING