Cholesterol metabolism and glaucoma: Modulation of Muller cell membrane organization by 24S-hydroxycholesterol.

@article{Gambert2017CholesterolMA,
  title={Cholesterol metabolism and glaucoma: Modulation of Muller cell membrane organization by 24S-hydroxycholesterol.},
  author={S{\'e}gol{\`e}ne Gambert and Pierre-Henry Gabrielle and Elodie A. Y. Masson and Elise Leger-Charnay and Arthur Ferrerro and Arthur Vannier and Cl{\'e}ment Gendrault and M{\'e}line Lachot and Catherine Creuzot-Garcher and Alain M Bron and St{\'e}phane Gr{\'e}goire and Laurent Lecl{\`e}re and Lucy Martine and G{\'e}raldine Lucchi and Caroline Truntzer and Delphine Pecqueur and Lionel Br{\'e}tillon},
  journal={Chemistry and physics of lipids},
  year={2017},
  volume={207 Pt B},
  pages={
          179-191
        }
}
Glaucoma is a progressive and irreversible blinding neuropathy that is characterized by the loss of retinal ganglion cells (RGCs). Muller Glial Cell (MGC) activation is induced in retinal gliosis. MGCs are the most numerous glial cells in the retina and one of their roles is to sustain cholesterol homeostasis. 24S-hydroxycholesterol (24S-OHC) is one of the form of cholesterol elimination from the retina and is overexpressed during glaucoma. The objective of this study was to determine whether… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS