Cholesterol level, statin use and Alzheimer's disease in adults with Down syndrome

@article{Zigman2007CholesterolLS,
  title={Cholesterol level, statin use and Alzheimer's disease in adults with Down syndrome},
  author={Warren B. Zigman and Nicole S Schupf and Edmund C Jenkins and Tiina K. Urv and W. Silverman},
  journal={Neuroscience Letters},
  year={2007},
  volume={416},
  pages={279-284}
}
Adults with Down syndrome (DS) are at significantly higher risk of Alzheimer's disease (AD) than the general population, but there is considerable variability in age at onset. This study tested the hypothesis that total cholesterol (TC) levels are related to vulnerability, and that the use of statins may decrease risk. The relation of TC level and statin use to risk of AD was investigated in 123 Caucasian adults with DS. Evaluations included serial assessments of cognitive, adaptive and… CONTINUE READING
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