Cholesterol feeding exacerbates myocardial injury in Zucker diabetic fatty rats.

@article{Hoshida2000CholesterolFE,
  title={Cholesterol feeding exacerbates myocardial injury in Zucker diabetic fatty rats.},
  author={Shiro Hoshida and Nobushige Yamashita and Kinya Otsu and Tsunehiko Kuzuya and Masatsugu Hori},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2000},
  volume={278 1},
  pages={
          H256-62
        }
}
  • Shiro Hoshida, Nobushige Yamashita, +2 authors Masatsugu Hori
  • Published in
    American journal of…
    2000
  • Medicine
  • We measured infarct size after coronary occlusion (30 min) and reperfusion (24 h) in genetic non-insulin-dependent Zucker diabetic fatty (ZDF) rats with and without 4-wk cholesterol feeding. Infarct size was similar in ZDF rats and lean control rats but was significantly larger in cholesterol-fed diabetic rats than in cholesterol-fed lean rats (P < 0.05). Plasma levels of glucose, insulin, and triglycerides were significantly higher in diabetic rats and were not influenced by cholesterol… CONTINUE READING

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    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 39 REFERENCES

    A nitric oxide donor reverses myocardial injury in rabbits with acute hypercholesterolemia.

    VIEW 4 EXCERPTS

    Nitric oxide synthase protects the heart against ischemia-reperfusion injury in rabbits.

    VIEW 1 EXCERPT