Corpus ID: 16635830

Cholesterol enrichment enhances expression of sterol-carrier protein-2: implications for its function in intracellular cholesterol trafficking.

@article{Kraemer1995CholesterolEE,
  title={Cholesterol enrichment enhances expression of sterol-carrier protein-2: implications for its function in intracellular cholesterol trafficking.},
  author={R. Kraemer and K. Pomerantz and S. Kesav and T. J. Scallen and D. Hajjar},
  journal={Journal of lipid research},
  year={1995},
  volume={36 12},
  pages={
          2630-8
        }
}
Cholesterol enrichment of vascular smooth muscle cells, as occurs under conditions of hypercholesterolemia and atherosclerosis, is accompanied by specific changes in cholesterol metabolism and in intracellular cholesterol trafficking. Sterol-carrier protein-2 (SCP2), an intracellular lipid binding protein, enhances the activation of enzymes involved in cholesterol metabolism. It may also enhance cholesterol efflux by regulating the size of the "fast" cholesterol pool available for efflux to… Expand
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References

SHOWING 1-10 OF 73 REFERENCES
Sterol carrier protein 2: A role in steroid hormone synthesis?
  • 69
Sterol carrier and lipid transfer proteins.
  • 103
Sterol carrier protein2 (SCP2)-like protein in rat aorta.
  • 9
...
1
2
3
4
5
...