Cholesterol enhances classical conditioning of the rabbit heart rate response.

@article{Schreurs2007CholesterolEC,
  title={Cholesterol enhances classical conditioning of the rabbit heart rate response.},
  author={Bernard G. Schreurs and Carrie A. Smith-Bell and Deya S Darwish and Desheng Wang and Lauren B. Burhans and Jimena Gonzales-Joekes and Stephen Deci and Goran Stankovi{\'c} and D. L. Sparks},
  journal={Behavioural brain research},
  year={2007},
  volume={181 1},
  pages={52-63}
}
The cholesterol-fed rabbit is a model of atherosclerosis and has been proposed as an animal model of Alzheimer's disease. Feeding rabbits cholesterol has been shown to increase the number of beta amyloid immunoreactive neurons in the cortex. Addition of copper to the drinking water of cholesterol-fed rabbits can increase this number still further and may lead to plaque-like structures. Classical conditioning of the nictitating membrane response in cholesterol-fed rabbits is retarded in the… CONTINUE READING
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