Cholesterol efflux capacity, high-density lipoprotein function, and atherosclerosis.


BACKGROUND High-density lipoprotein (HDL) may provide cardiovascular protection by promoting reverse cholesterol transport from macrophages. We hypothesized that the capacity of HDL to accept cholesterol from macrophages would serve as a predictor of atherosclerotic burden. METHODS We measured cholesterol efflux capacity in 203 healthy volunteers who… (More)
DOI: 10.1056/NEJMoa1001689


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