• DOI:10.1126/science.aar7369
Corpus ID: 3257111

Cholesterol crystals impede nerve repair

@article{Chen2018CholesterolCI,
  title={Cholesterol crystals impede nerve repair},
  author={Yanan Chen and B. Popko},
  journal={Science},
  year={2018},
  volume={359},
  pages={635 - 636}
}

Yanan Chen, B. Popko

Published 2018

Medicine

Science

Cholesterol deposits in phagocytic cells disrupt the repair of demyelinated axons Damage to the myelin sheath that surrounds nerve axons represents the pathological hallmark of the neurological disorder multiple sclerosis (MS) and is thought to contribute to a number of other nervous system maladies (1). Remyelination, a regenerative process that forms new myelin sheaths around demyelinated axons, restores nerve function and reverses the clinical manifestations associated with demyelination (2… CONTINUE READING

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