Cholesterol as a bioregulator in the development and inhibition of leukemia.

@article{Inbar1974CholesterolAA,
  title={Cholesterol as a bioregulator in the development and inhibition of leukemia.},
  author={Michael Inbar and Meir Shinitzky},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1974},
  volume={71 10},
  pages={
          4229-31
        }
}
  • Michael Inbar, Meir Shinitzky
  • Published 1974
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
  • Leukemia in mice and humans is accompanied by a marked deficiency of unesterified cholesterol in the surface membrane of leukemic cells as compared to normal leukocytes. This deficiency induces a significant reduction in their membrane microviscosity. Since cholesterol in the cell surface membrane is exchangeable with cholesterol in the serum lipoproteins, concomitant to the cellular deficiency of cholesterol, the average level of cholesterol in the blood serum of leukemic patients is… CONTINUE READING

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