Cholesterol and phospholipid metabolism in macrophages.

  title={Cholesterol and phospholipid metabolism in macrophages.},
  author={Ira Tabas},
  journal={Biochimica et biophysica acta},
  volume={1529 1-3},
  • Ira Tabas
  • Published 2000 in Biochimica et biophysica acta
Cholesterol-loaded macrophages are present at all stages of atherogenesis, and recent in vivo data indicate that these cells play important roles in both early lesion development and late lesion complications. To understand how these cells promote atherogenesis, it is critical that we understand how lesional macrophages interact with subendothelial lipoproteins, the consequences of this interaction, and the impact of subsequent intracellular metabolic events. In the arterial wall, macrophages… CONTINUE READING

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