Cholesterol and male fertility: what about orphans and adopted?

  title={Cholesterol and male fertility: what about orphans and adopted?},
  author={Salwan Maqdasy and Marine Baptissart and Aur{\'e}lie V{\'e}ga and Silv{\`e}re Baron and Jean Marc A Lobaccaro and David H. Volle},
  journal={Molecular and cellular endocrinology},
  volume={368 1-2},
The link between cholesterol homeostasis and male fertility has been clearly suggested in patients who suffer from hyperlipidemia and metabolic syndrome. This has been confirmed by the generation of several transgenic mouse models or in animals fed with high cholesterol diet. Next to the alteration of the endocrine signaling pathways through steroid receptors (androgen and estrogen receptors); "orphan" and "adopted" nuclear receptors, such as the Liver X Receptors (LXRs), the Proliferating… CONTINUE READING


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