Cholesterol and cataracts.

  title={Cholesterol and cataracts.},
  author={Richard J. Cenedella},
  journal={Survey of ophthalmology},
  volume={40 4},
Inherited defects in enzymes of cholesterol metabolism and use of drugs which inhibit lens cholesterol biosynthesis can be associated with cataracts in animals and man. The basis of this relationship apparently lies in the need of the lens to satisfy its sustained requirement for cholesterol by on-site synthesis, and impairing this synthesis can lead to alteration of lens membrane structure. Lens membrane contains the highest cholesterol content of any known membrane. The Smith-Lemli-Opitz… CONTINUE READING
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