Cholesterol and Heart Failure: Is There an Important Connection?

@article{Francis2017CholesterolAH,
  title={Cholesterol and Heart Failure: Is There an Important Connection?},
  author={Gordon S. Francis},
  journal={Journal of the American College of Cardiology},
  year={2017},
  volume={70 17},
  pages={
          2137-2138
        }
}
T he BIOSTAT-CHF (BIOlogy Study to TAilored Treatment in Chronic Heart Failure) study by Bayes-Genis et al. (1) in this issue of the Journal describes the prognostic value of a new biotarget in the management of atherosclerosis progression: the proprotein convertase subtilisin/kexin type 9 (PCSK9), and its interaction or “axis” with low-density lipoprotein receptors (LDLRs) on the surface of hepatocytes. Although it is well known that PCSK9 and LDLR are associated with atherosclerotic risk (2… CONTINUE READING
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