Cholesterol affects spectrin-phospholipid interactions in a manner different from changes resulting from alterations in membrane fluidity due to fatty acyl chain composition.

@article{Diakowski2006CholesterolAS,
  title={Cholesterol affects spectrin-phospholipid interactions in a manner different from changes resulting from alterations in membrane fluidity due to fatty acyl chain composition.},
  author={Witold Diakowski and Łukasz Ozimek and Ewa Bielska and Sylwia Bem and Marek Langner and Aleksander F. Sikorski},
  journal={Biochimica et biophysica acta},
  year={2006},
  volume={1758 1},
  pages={4-12}
}
We previously showed that erythrocyte and brain spectrins bind phospholipid vesicles and monolayers prepared from phosphatidylethanolamine and phosphatidylserine and their mixtures with phosphatidylcholine (Review: A.F. Sikorski, B. Hanus-Lorenz, A. Jezierski, A. R. Dluzewski, Interaction of membrane skeletal proteins with membrane lipid domain, Acta Biochim. Polon. 47 (2000) 565). Here, we show how changes in the fluidity of the phospholipid monolayer affect spectrin-phospholipid interaction… CONTINUE READING