Cholesterol-Lowering Activity of Naringenin via Inhibition of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase and Acyl Coenzyme A:Cholesterol Acyltransferase in Rats

@article{Lee1999CholesterolLoweringAO,
  title={Cholesterol-Lowering Activity of Naringenin via Inhibition of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase and Acyl Coenzyme A:Cholesterol Acyltransferase in Rats},
  author={S. Lee and Y. Park and K. H. Bae and S. H. Bok and Y. K. Kwon and Eun seok Lee and M. S. Choi},
  journal={Annals of Nutrition and Metabolism},
  year={1999},
  volume={43},
  pages={173 - 180}
}
  • S. Lee, Y. Park, +4 authors M. S. Choi
  • Published 1999
  • Medicine
  • Annals of Nutrition and Metabolism
  • The effects of dietary supplementation of a citrus bioflavonoid, naringenin, on the cholesterol metabolism were studied. For 42 days male rats were fed a 1% (wt/wt) high-cholesterol diet with or without a naringenin supplementation (0.1%, wt/wt) to study its effect on plasma lipid levels, hepatic lipid contents, activities of hepatic acyl coenzyme A:cholesterol O-acyltransferase (ACAT) and 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, and the excretion of fecal neutral sterols… CONTINUE READING

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