• Corpus ID: 87724821

Cholesterol Efflux from Macrophages Mediated by High Density Lipoprotein-3

  title={Cholesterol Efflux from Macrophages Mediated by High Density Lipoprotein-3},
  author={Chen Pei},
  • Chen Pei
  • Published 2000
  • Biology, Chemistry, Medicine
Aim To study the mechanism of cholesterol efflux from rat peritoneal macrophages mediated by high density lipoprotein-3(HDL 3). Methods Modification of HDL 3 by N-acetylimidazole blocked interaction between HDL and its cellular receptor. FITC labeled HDL 3 were used to observed the cellular metabolic process of HDL 3. Results BSA (control group) mediated 2.9% cellular cholesterol efflux from the cells. In HDL 3 group and N-acetylimidazole-HDL 3 group,they were 40.7% and 8.7% respectively. After… 
High density lipoprotein receptors, binding proteins, and ligands.
  • N. Fidge
  • Biology
    Journal of lipid research
  • 1999
Several HDL binding proteins, quite disparate in structure, have recently been cloned and their role in HDL metabolism is currently being assessed and growing evidence for the involvement of lipid-poor apoA-I as a mediator of such pathways is also discussed.