Cholesterol 7alpha-hydrolase (CYP7A1) c.-278A>C promoter polymorphism in gallstone disease patients.

Abstract

There is growing evidence that gallstone formation may be genetically determined. Cholesterol 7alpha-hydrolase (CYP7A1) is an enzyme that catalyzes the first, rate-limiting reaction of cholesterol catabolic pathway. Recently, a common c.-278A>C polymorphism (rs3808607:G>T) has been described in CYP7A1 gene, associated with altered plasma lipid levels. The… (More)
DOI: 10.1089/gte.2007.0067

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@article{Juzyszyn2008Cholesterol7, title={Cholesterol 7alpha-hydrolase (CYP7A1) c.-278A>C promoter polymorphism in gallstone disease patients.}, author={Zygmunt Juzyszyn and Mateusz Kurzawski and Agnieszka Lener and Andrzej Modrzejewski and Andrzej Pawlik and Marek Droździk}, journal={Genetic testing}, year={2008}, volume={12 1}, pages={97-100} }