Cholestasis and metabolic bone disease – a clinical review

@article{Gasser2008CholestasisAM,
  title={Cholestasis and metabolic bone disease – a clinical review},
  author={Rudolf Wolfgang Gasser},
  journal={Wiener Medizinische Wochenschrift},
  year={2008},
  volume={158},
  pages={553-557}
}
Die hepatische Osteodystrophie, eine metabolische Knochenerkrankung – vorwiegend Osteoporose/Osteopenie, gelegentlich Osteomalazie – ist eine gravierende extrahepatische Manifestation einer chronisch cholestatischen Lebererkrankung. Eine verminderte Knochenmineraldichte wird in bis zu 60 % der Patienten mit chronischer Lebererkrankung gefunden, atraumatische Frakturen in etwa 20 %. Eine verminderte Knochenneubildung und eine verstärkte Knochenresorption charakterisieren die hepatische… CONTINUE READING

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