Cholera Toxin Increases the Rate of Antigen-stimulated Calcium Influx in Rat Basophilic Leukemia Cells *

@inproceedings{NarasimhanS2001CholeraTI,
  title={Cholera Toxin Increases the Rate of Antigen-stimulated Calcium Influx in Rat Basophilic Leukemia Cells *},
  author={Vikram NarasimhanS and David HolowkaQ and Clare FewtrelllI and Barbara BairdQ},
  year={2001}
}
  • Vikram NarasimhanS, David HolowkaQ, +1 author Barbara BairdQ
  • Published 2001
Cholera toxin pretreatment has been found to cause a %fold increase in the initial rate of antigen-stimulated secretion of serotonin from rat basophilic leukemia (RBL) cells. Under similar conditions, cholera toxin enhances the antigen-stimulated rise in cytoplasmic free ionized calcium levels and causes a 2-3fold increase in the rate of antigen-stimulated influx of 4sCa. In intact RBL cells cholera toxin pretreatment potentiates the antigen-stimulated production of inositol phosphates, but in… CONTINUE READING

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