Cholecystokinin stimulates the down-regulation of CTP:phosphocholine cytidylyltransferase in pancreatic acinar cells.

@article{Groblewski1995CholecystokininST,
  title={Cholecystokinin stimulates the down-regulation of CTP:phosphocholine cytidylyltransferase in pancreatic acinar cells.},
  author={Guy E. Groblewski and Yanlin Wang and Stephen A. Ernst and Claudia Kent and Jennifer A E Williams},
  journal={The Journal of biological chemistry},
  year={1995},
  volume={270 3},
  pages={1437-42}
}
Stimulation of rat pancreatic acinar cells with cholecystokinin (CCK) is known to result in a significant inhibition of CTP:phosphocholine cytidylyltransferase (CT), a rate-limiting enzyme in phosphatidylcholine biosynthesis. Immunoprecipitation of CT from 32P-labeled acinar cells revealed that CCK treatment also caused a marked reduction in CT phosphate… CONTINUE READING