Cholecystokinin receptors mediate enhanced memory retention produced by feeding and gastrointestinal peptides

@article{Flood1989CholecystokininRM,
  title={Cholecystokinin receptors mediate enhanced memory retention produced by feeding and gastrointestinal peptides},
  author={James Flood and J Eileen Morley},
  journal={Peptides},
  year={1989},
  volume={10},
  pages={809-813}
}
Ingestion of food in mice following training on T-maze footshock avoidance enhanced memory retention when tested 7 days later. This eating-induced improvement of retention was blocked by a specific cholecystokinin antagonist, L-364,718. The cholecystokinin antagonist prevented enhancement of memory retention resulting from posttraining administration of the gastrointestinal hormones, cholecystokinin, bombesin or gastrin releasing peptide. L-364,718 neither impaired or improved retention when… CONTINUE READING