Cholecystokinin and GABA interaction in the dorsal hippocampus of rats in the elevated plus-maze test of anxiety.

@article{Rezayat2005CholecystokininAG,
  title={Cholecystokinin and GABA interaction in the dorsal hippocampus of rats in the elevated plus-maze test of anxiety.},
  author={Mehdi Rezayat and Ali Roohbakhsh and Mohammad Reza Zarrindast and Roohollah Massoudi and Bijan Djahanguiri},
  journal={Physiology & behavior},
  year={2005},
  volume={84 5},
  pages={775-82}
}
In the present study, we have investigated the effects and interaction of CCK and GABAergic systems in the dorsal hippocampus of rats using the elevated plus-maze test of anxiety. Bilateral injection of different doses of CCK(8s) (0.01, 0.05 and 0.1 microg/rat) into the dorsal hippocampus (intra-CA1) decreased percentage of open arm time (%OAT) and open arm entries (%OAE) that are representative of anxiogenic-like behavior. The bilateral injection of three doses of LY225910, a selective CCK2… CONTINUE READING