Cholecystokinin activates CCKB-receptor-mediated Ca-signaling in hippocampal astrocytes.

@article{Mller1997CholecystokininAC,
  title={Cholecystokinin activates CCKB-receptor-mediated Ca-signaling in hippocampal astrocytes.},
  author={W D M{\"u}ller and Uwe F Heinemann and Karin Berlin},
  journal={Journal of neurophysiology},
  year={1997},
  volume={78 4},
  pages={1997-2001}
}
Cholecystokinin-8S (CCK-8S) is the most abundant neuropeptide in the mammalian cortex and the limbic system; however, its physiological functions remained largely obscure. We studied effects of CCK on astrocytic Ca signaling, which has met considerable interest as a second messenger in astrocytic-neuronal signaling, by digital ratio-imaging of Fura-2/AM loaded rat and mouse hippocampal astrocytes in dissociated culture. Superfusion of CCK-8S (5-50 nM for 2 min) evoked repetitive Ca increases of… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 13 references

Electrophysiological of mammalian brain cells

E. HÖSLI, T. WINTER, H. AND KASER
Science • 1994

The observation of various forms plex through CCKB sites

P. BRANCHEREAU, J. CHAMPAGNAT
Neuroreport • 1992

[ 3 H ] PD 140376 : a novel and highly SNYDER , S . H . AND BREDT , D . S . Nitric oxide as a neuronal messenger . selective antagonist radioligand for the cholecystokininB / gastrin receptor Trends

J. HUGHES, G. N. WOODRUFF
Pharmacol . Sci . • 1991

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