Cholecystokinin, gastrin, cholecystokinin/gastrin receptors, and bitter taste receptor TAS2R14: trophoblast expression and signaling.

@article{Taher2019CholecystokininGC,
  title={Cholecystokinin, gastrin, cholecystokinin/gastrin receptors, and bitter taste receptor TAS2R14: trophoblast expression and signaling.},
  author={Sh{\`e}dy Taher and Yamilette Borja and Luc{\'i}a Cabanela and Vincent J Costers and Morgan Carson-Marino and Julie C Bailes and Biswadeep Dhar and Mark T Beckworth and Mar{\'i}a Bel{\'e}n Rabaglino and Emiel D Post Uiterweer and Kirk P Conrad},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2019},
  volume={316 5},
  pages={
          R628-R639
        }
}
  • Shèdy Taher, Yamilette Borja, +8 authors Kirk P Conrad
  • Published 2019
  • Medicine, Biology
  • American journal of physiology. Regulatory, integrative and comparative physiology
  • We investigated expression of cholecystokinin (CCK) in humans and mice, and the bitter taste receptor TAS2R14 in the human placenta. Because CCK and gastrin activate the CCKBR receptor, we also explored placental gastrin expression. Finally, we investigated calcium signaling by CCK and TAS2R14. By RT-PCR, we found CCK/Cck and GAST/Gast mRNA expression in both normal human and mouse placentas, as well as in human trophoblast cell lines (TCL). Although both Cckar and -br mRNA were expressed in… CONTINUE READING

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