Cholangiocarcinoma and High-Grade Dysplasia in Young Patients with Primary Sclerosing Cholangitis

  title={Cholangiocarcinoma and High-Grade Dysplasia in Young Patients with Primary Sclerosing Cholangitis},
  author={Roy P Liu and Kristen E. Cox and Stephen L Guthery and Linda Book and Benjamin J Witt and Barbara Chadwick and Douglas G Adler},
  journal={Digestive Diseases and Sciences},
Cholangiocarcinoma (CCA) is very often an adulthood disease with primary sclerosing cholangitis (PSC) as one of the risk factors. It is rarely seen in the pediatric population, and when it is diagnosed before adulthood, it can be associated with PSC as well as HIV infection, biliary atresia, radiation therapy, and choledochal cyst. Although there have been some case reports of pediatric CCA, cases of childhood CCA associated with PSC are still relatively rare. To describe the clinical and… CONTINUE READING
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