Cholangiocarcinoma: Biology, Clinical Management, and Pharmacological Perspectives

  title={Cholangiocarcinoma: Biology, Clinical Management, and Pharmacological Perspectives},
  author={Rocio I R Macias},
  booktitle={ISRN hepatology},
Cholangiocarcinoma (CCA), or tumor of the biliary tree, is a rare and heterogeneous group of malignancies associated with a very poor prognosis. Depending on their localization along the biliary tree, CCAs are classified as intrahepatic, perihilar, and distal, and these subtypes are now considered different entities that differ in tumor biology, the staging system, management, and prognosis. When diagnosed, an evaluation by a multidisciplinary team is essential; the team must decide on the best… CONTINUE READING
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Co - carcinogenic effects of intrahepatic bile acid accumulation in cholangiocarcinoma development

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