Chlorpropamide and lipid metabolism of rat and human adipose tissue in vitro.

@article{Ostman1970ChlorpropamideAL,
  title={Chlorpropamide and lipid metabolism of rat and human adipose tissue in vitro.},
  author={J. S. Ostman and Suad Efendić and Peter Arner},
  journal={Acta medica Scandinavica},
  year={1970},
  volume={187 1-2},
  pages={
          11-6
        }
}
  • J. S. Ostman, Suad Efendić, Peter Arner
  • Published 1970
  • Medicine, Biology
  • Acta medica Scandinavica
  • . Lipolysis measured as glycerol release from rat adipose tissue in vitro was inhibited by chlorpropamide. This antilipolytic effect was independent of the addition of glucose to the incubation medium. At the same time chlorpropamide decreased the re-esterification of FFA formed by lipolysis. This inhibitory effect was more pronounced in tissue incubated in medium with glucose present. Since lipolysis as well as re-esterification of FFA is accelerated by glucose, present data would indicate… CONTINUE READING