Chlorpromazine methiodide acts at the vestibular nuclear complex to induce barrel rotation in the rat.

Barrel rotation is a unique motor response observed in rats in which, following an intracerebral injection, the animal develops a twist about the long axis and rolls laterally repeatedly. The response was first described following injection of somatostatin. We have previously shown that 'experimental dystonia' in rats induced by intraventricular… (More)