Chlorpromazine inhibits mitosis of mammalian cells.

  title={Chlorpromazine inhibits mitosis of mammalian cells.},
  author={George B. Boder and Donald C. Paul and Daniel K. C. Williams},
  journal={European journal of cell biology},
  volume={31 2},
Chlorpromazine (CPZ) at minimally effective concentrations accumulates mammalian cells in mitosis without lethal effects on the cells. Star-metaphase morphology similar to effects seen with classical antimitotic compounds probably results from the preferential action of CPZ on a specific class of microtubules--the pole-to-pole microtubules of the mitotic… CONTINUE READING