Chlorproguanil-dapsone for treatment of drug-resistant falciparum malaria in Tanzania.

  title={Chlorproguanil-dapsone for treatment of drug-resistant falciparum malaria in Tanzania.},
  author={Theonest K. Mutabingwa and Alexis M Nzila and Edward K Mberu and Eunice Nduati and Peter A. Winstanley and Ellen Hills and William M. Watkins},
  volume={358 9289},
BACKGROUND Resistance to the affordable malaria treatments chloroquine and pyrimethamine-sulfadoxine is seriously impeding malaria control through treatment in east Africa. We did an open, alternate drug allocation study to assess the efficacy of chlorproguanil-dapsone in the treatment of falciparum malaria clinically resistant to pyrimethamine-sulfadoxine. METHODS Children younger than 5 years with non-severe falciparum malaria, attending Muheza district hospital in Tanzania, were treated… CONTINUE READING


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