Chloroquine exerts antitumor effects on NB4 acute promyelocytic leukemia cells and functions synergistically with arsenic trioxide.

@article{Liu2018ChloroquineEA,
  title={Chloroquine exerts antitumor effects on NB4 acute promyelocytic leukemia cells and functions synergistically with arsenic trioxide.},
  author={Shousheng Liu and Xiuyu Cai and Liangping Xia and Chang Hong Jiang and Ping Chen and Xiaopai Wang and Bei Zhang and Hong Yun Zhao},
  journal={Oncology letters},
  year={2018},
  volume={15 2},
  pages={2024-2030}
}
Chloroquine (CQ) has been confirmed to exhibit antitumor effects on different types of cancer cell, but whether it exerts the same effect on acute promyelocytic leukemia (APL) cells remains to be confirmed. In the present study, the effects of various concentrations of CQ on the growth, apoptosis and cell cycle distribution of NB4 cells, as well as the… CONTINUE READING