Chloroquine cardiomyopathy – a review of the literature

  title={Chloroquine cardiomyopathy – a review of the literature},
  author={Ernst T{\"o}nnesmann and R. Kandolf and T. Lewalter},
  journal={Immunopharmacology and Immunotoxicology},
  pages={434 - 442}
  • Ernst Tönnesmann, R. Kandolf, T. Lewalter
  • Published 2013
  • Medicine
  • Immunopharmacology and Immunotoxicology
  • Abstract Chloroquine and hydroxychloroquine are still used for the prevention and treatment of malaria. Moreover, they are experiencing a renaissance in the long-term therapy of connective tissue diseases (particularly in systemic lupus erythematosus). They induce a lysosomal dysfunction with an accumulation of pathologic metabolic products, which can be seen in ultrastructural histology as pathognomonic cytoplasmic inclusion bodies. Due to its lower toxicity, hydroxychloroquine is the form… CONTINUE READING
    95 Citations
    [Early cardiotoxicity of Hydroxychloroquine].
    • 2
    • Highly Influenced
    Hydroxychloroquine in systemic lupus erythematosus (SLE)
    • 94
    Hydroxychloroquine-induced cardiomyopathy in a patient with limited cutaneous systemic sclerosis
    • 5


    Chloroquine related cardiac toxicity.
    • 40
    A Case of Chloroquine-Induced Cardiomyopathy That Presented as Sick Sinus Syndrome
    • 15
    • PDF
    Cardiac toxicity secondary to long term treatment with chloroquine
    • 52
    • PDF
    Hydroxychloroquine-induced restrictive cardiomyopathy.
    • 33
    • PDF