Chloroquine–Primaquine versus Chloroquine Alone to Treat Vivax Malaria in Afghanistan: An Open Randomized Superiority Trial

@inproceedings{Awab2017ChloroquinePrimaquineVC,
  title={Chloroquine–Primaquine versus Chloroquine Alone to Treat Vivax Malaria in Afghanistan: An Open Randomized Superiority Trial},
  author={Ghulam Rahim Awab and Mallika Imwong and Germana Bancone and Atthanee Jeeyapant and Nicholas P J Day and Nicholas J White and Charles J Woodrow},
  booktitle={The American journal of tropical medicine and hygiene},
  year={2017}
}
Afghanistan's national guidelines recommend primaquine (PQ) for radical treatment of Plasmodium vivax malaria, but this is rarely implemented because of concerns over potential hemolysis in patients who have G6PD deficiency. Between August 2009 and February 2014, we conducted an open-label, randomized controlled trial of chloroquine (CQ) alone versus chloroquine plus primaquine (0.25 mg base/kg/day for 14 days) (CQ+PQ) in patients aged 6 months and older with microscopy confirmed P. vivax… CONTINUE READING
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