Chloromethane-induced genes define a third C1 utilization pathway in Methylobacterium chloromethanicum CM4.

@article{Studer2002ChloromethaneinducedGD,
  title={Chloromethane-induced genes define a third C1 utilization pathway in Methylobacterium chloromethanicum CM4.},
  author={Alex Studer and Craig McAnulla and Rainer B{\"u}chele and Thomas Leisinger and St{\'e}phane Vuilleumier},
  journal={Journal of bacteriology},
  year={2002},
  volume={184 13},
  pages={3476-84}
}
Methylobacterium chloromethanicum CM4 is an aerobic alpha-proteobacterium capable of growth with chloromethane as the sole carbon and energy source. Two proteins, CmuA and CmuB, were previously purified and shown to catalyze the dehalogenation of chloromethane and the vitamin B12-mediated transfer of the methyl group of chloromethane to tetrahydrofolate. Three genes located near cmuA and cmuB, designated metF, folD and purU and encoding homologs of methylene tetrahydrofolate (methylene-H4folate… CONTINUE READING