Chloroform-induced oxidative stress in rat liver: Implication of metallothionein.

Current studies evaluated the effect of acute and subacute exposure to chloroform (CHCl(3)) on rat liver and the implication of oxidative stress. For this purpose, different doses of CHCl(3) (150, 300 and 450 mg/kg bw) were administered intraperitoneally (ip) to male Wistar rats. Malondialdehyde (MDA), glutathione (GSH), reduced cytochrome c and… CONTINUE READING