Chloride transport in the freshwater protozoanTetrahymena pyriformis


Tetrahymena accumulates36Cl− in both nutrient and salt media. Up to 80% of the initial net36Cl− influx was inhibited by the anion exchange inhibitor DIDS (4,4′-diisothiocyano-2,2′-stilbene-disulfonic acid). The ‘loop’ diuretic, bumetanide, had no effect. A DIDS-sensitive anion exchange system is proposed to regulate the cytoplasmic Cl− concentration… (More)
DOI: 10.1007/BF01939895

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