Chloride movements in human neutrophils. Diffusion, exchange, and active transport

@article{Simchowitz1986ChlorideMI,
  title={Chloride movements in human neutrophils. Diffusion, exchange, and active transport},
  author={Louis Simchowitz and Paul De Weer},
  journal={The Journal of General Physiology},
  year={1986},
  volume={88},
  pages={167 - 194}
}
Chloride content and fluxes were measured in isolated resting human peripheral polymorphonuclear leukocytes. The intracellular Cl concentration of cells kept at 37 degrees C in 148 mM Cl media was approximately 80 meq/liter cell water, fourfold higher than expected for passive distribution at the cell's estimated membrane potential (approximately -53 mV). All intracellular Cl was rapidly exchangeable with external 36Cl. Cells lost Cl exponentially into Cl-free media, and reaccumulated it when… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 28 extracted citations

Chloride flux in phagocytes.

Immunological reviews • 2016
View 1 Excerpt

References

Publications referenced by this paper.
Showing 1-10 of 10 references

Regulation of intracellular pH in human neutrophils

The Journal of general physiology • 1985
View 4 Excerpts

Energy metabolism of human neutrophils during phagocytosis.

The Journal of clinical investigation • 1982
View 1 Excerpt

Epithelia l cell volume modulation and regulation

H. H. Ussing
journal of Membrane Biology • 1982

Organic anion transport in red blood cells

R Motais
1977
View 2 Excerpts

Transport through red cell membranes

Sachs, R J., P . A . Knauf, P . B . Dunham
The Red Blood Cell • 1974

The distinction, by means of tracers, between active transport and diffusion . The transfer of iodide across the isolated frog skin

Ussing, H H.
Acta Physiologica Scandinavica • 1949

Potential, Impedance, and Rectification in Membranes

The Journal of general physiology • 1943
View 1 Excerpt

Ueber die Permeabilitat der Leukocyten fur Ionen

D. E. Goldman
Pflugers Archiv European Journal ofPhysiology . • 1930

Mineralzusammensetzung der Blutplattchen and weissen Blutk 6 rperchen

W. Fleischmann
Zeitschrift fiir Biologie . • 1929

Similar Papers

Loading similar papers…