Chloride dependent intracellular pH increase induced by bepridil in human red blood cells: a possible involvement in correction of ischemic acidosis.

@article{Kovacic1993ChlorideDI,
  title={Chloride dependent intracellular pH increase induced by bepridil in human red blood cells: a possible involvement in correction of ischemic acidosis.},
  author={Herv{\'e} Kovacic and Philippe Gallice and Micha{\"e}l Sarrazin and Aim{\'e} D. Crevat},
  journal={The Journal of pharmacology and experimental therapeutics},
  year={1993},
  volume={267 3},
  pages={1509-14}
}
Inhibitors of Na+/H+ exchanger are reported to exert an anti-ischemic effect. Some calcium antagonists and particularly bepridil are commonly used as anti-ischemic agents. Therefore, in this study, we test the hypothesis that protective effect against ischemia may occur at least in part through an action on Na+/H+ exchanger. The effect of some calcium… CONTINUE READING