Chlorhexidine skin or cord care for prevention of mortality and infections in neonates.

@article{Sinha2015ChlorhexidineSO,
  title={Chlorhexidine skin or cord care for prevention of mortality and infections in neonates.},
  author={Anju Pradhan Sinha and Sunil Sazawal and Alok Pradhan and Siddarth Ramji and Newton Opiyo},
  journal={The Cochrane database of systematic reviews},
  year={2015},
  volume={3},
  pages={
          CD007835
        }
}
BACKGROUND Affordable, feasible and efficacious interventions to reduce neonatal infections and improve neonatal survival are needed. Chlorhexidine, a broad spectrum topical antiseptic agent, is active against aerobic and anaerobic organisms and reduces neonatal bacterial colonisation and may reduce infection. OBJECTIVES To evaluate the efficacy of neonatal skin or cord care with chlorhexidine versus routine care or no treatment for prevention of infections in late preterm or term newborn… 
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Chlorhexidine cord application significantly reduces neonatal sepsis and mortality in developing countries and the importance of including chlorhexidine Cord application into the essential newborn care in the setting with high burden of neonatal mortality is stressed.
Chlorhexidine and newborn omphalitis and mortality - Authors' reply.
TLDR
Stephen Hodgins says that cord application of chlorhexidine protects infants against omphalitis equally after birth at home or in hospital, and that the authors were incorrect to say that it was not eff ective for infants born in hospital.
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Application of chlorhexidine to newborn umbilical cord stumps, significantly reduce the incidences of both neonatal mortality and omphalitis.
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TLDR
It is shown that chlor hexidine cleansing could significantly reduce central line-associated bloodstream infection in neonates based on large-sample studies, and more studies are needed to determine the optimal concentration and frequency of chlorhexidine cleansing.
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TLDR
A parallel group feasibility randomised controlled trial comparing vaginal cleansing using chlorhexidine gluconate versus no cleansing at CS to reduce infection and develops women centred outcomes of wellbeing after delivery.
Application of 4% chlorhexidine to the umbilical cord stump of newborn infants in lower income countries: a systematic review and meta-analysis
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This systematic review found that topical application of 4% chlorhexidine to the umbilical cord stump of newborn infants in lower income countries significantly reduces the incidence of neonatal mortality.
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TLDR
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