Chlorhexidine-Alcohol versus Povidone-Iodine for Surgical-Site Antisepsis.

@article{Darouiche2010ChlorhexidineAlcoholVP,
  title={Chlorhexidine-Alcohol versus Povidone-Iodine for Surgical-Site Antisepsis.},
  author={Rabih O. Darouiche and Matthew J. Wall and Kamal M. F. Itani and Mary Francis Otterson and Alexandra Louise Webb and Matthew Carrick and H. J. Miller and Samir S. Awad and Cynthia T. Crosby and Michael C. Mosier and Atef Alsharif and David H. Berger},
  journal={The New England journal of medicine},
  year={2010},
  volume={362 1},
  pages={18-26}
}
BACKGROUND Since the patient's skin is a major source of pathogens that cause surgical-site infection, optimization of preoperative skin antisepsis may decrease postoperative infections. We hypothesized that preoperative skin cleansing with chlorhexidine-alcohol is more protective against infection than is povidone-iodine. METHODS We randomly assigned adults undergoing clean-contaminated surgery in six hospitals to preoperative skin preparation with either chlorhexidine-alcohol scrub or… CONTINUE READING
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