Chlordiazepoxide attenuates response suppression induced by corticotropin-releasing factor in the conflict test

@article{Britton1985ChlordiazepoxideAR,
  title={Chlordiazepoxide attenuates response suppression induced by corticotropin-releasing factor in the conflict test},
  author={Karen Thatcher Britton and Janet M Fain Morgan and Jean E. Rivier and Wylie Vale and George F. Koob},
  journal={Psychopharmacology},
  year={1985},
  volume={86},
  pages={170-174}
}
The role of corticotropin-releasing factor (CRF) in mediating the stress response was studied using a behavioral test in which anxiety or conflict influence performance. Rats implanted with intraventricular cannulae were tested in a Geller-Seifter conflict test modified for incremental shock. CRF produced a dose-dependent attenuation of punished and nonpunished responding in the conflict test. Chlordiazepoxide increased punished, but not unpunished, responding and produced a dose-dependent… CONTINUE READING

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SHOWING 1-10 OF 34 CITATIONS

The role of corticotropin-releasing factor in drug addiction.

  • Pharmacological reviews
  • 2001
VIEW 6 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

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  • The international journal of neuropsychopharmacology
  • 2011
VIEW 1 EXCERPT
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 31 REFERENCES

Benzodiazepines attenuate stimulated fl-endorphin release

KT Britton, RD Stewart, SC Risch
  • Psychopharmacol Bull
  • 1983
VIEW 1 EXCERPT

Effects of antidepressants, anxiogenic substances and benzodiazepine antagonists on the selfregulation of ICSS duration

S Gerhardt, JM Liebman
  • Soc Neurosci Abstr
  • 1983

Corticotropin-releasing factor produces behavioral activation rats

RE Sutton, GF Koob, M LeMoal, J Rivier, W Vale
  • Nature
  • 1982
VIEW 2 EXCERPTS