Chloramphenicol treatment for acute infective conjunctivitis in children in primary care: a randomised double-blind placebo-controlled trial.

@article{Rose2005ChloramphenicolTF,
  title={Chloramphenicol treatment for acute infective conjunctivitis in children in primary care: a randomised double-blind placebo-controlled trial.},
  author={Peter W. Rose and Anthony Harnden and Angela B. Brueggemann and Rafael Perera and Aziz Sheikh and Derrick W. Crook and David C Mant},
  journal={Lancet},
  year={2005},
  volume={366 9479},
  pages={37-43}
}
BACKGROUND One in eight schoolchildren have an episode of acute infective conjunctivitis every year. Standard clinical practice is to prescribe a topical antibiotic, although the evidence to support this practice is scarce. We undertook a randomised double-blind trial to compare the effectiveness of chloramphenicol eye drops with placebo in children with infective conjunctivitis in primary care. METHODS Our study included 326 children aged 6 months to 12 years with a clinical diagnosis of… CONTINUE READING
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