Chlamydomonas immunophilins and parvulins: survey and critical assessment of gene models.

@article{Vallon2005ChlamydomonasIA,
  title={Chlamydomonas immunophilins and parvulins: survey and critical assessment of gene models.},
  author={Olivier Vallon},
  journal={Eukaryotic cell},
  year={2005},
  volume={4 2},
  pages={230-41}
}
Cis-trans isomerization of the Xaa-Pro bond is an important step in protein folding and a critical determinant of protein structure (27). Peptidyl-prolyl cis-trans isomerases (PPIases or rotamases) belong to three unrelated families: FK506-binding proteins (FKBPs), cyclophilins, and parvulins. The first two families are collectively known as immunophilins because of their ability to tightly bind immunosuppressive drugs: cyclophilins bind cyclosporine A, while FKBPs bind the molecules rapamycin… CONTINUE READING