Chlamydomonas IFT172 Is Encoded by FLA11, Interacts with CrEB1, and Regulates IFT at the Flagellar Tip

@article{Pedersen2005ChlamydomonasII,
  title={Chlamydomonas IFT172 Is Encoded by FLA11, Interacts with CrEB1, and Regulates IFT at the Flagellar Tip},
  author={L. B. Pedersen and M. S. Miller and S. Geimer and Jeffery M. Leitch and J. Rosenbaum and D. Cole},
  journal={Current Biology},
  year={2005},
  volume={15},
  pages={262-266}
}
The transport of flagellar precursors and removal of turnover products from the flagellar tip is mediated by intraflagellar transport (IFT) , which is essential for both flagellar assembly and maintenance . Large groups of IFT particles are moved from the flagellar base to the tip by kinesin-2, and smaller groups are returned to the base by cytoplasmic dynein 1b. The IFT particles are composed of two protein complexes, A and B, comprising approximately 16-18 polypeptides. How cargo is unloaded… Expand

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