Chlamydia trachomatis infection modulates trophoblast cytokine/chemokine production.

  title={Chlamydia trachomatis infection modulates trophoblast cytokine/chemokine production.},
  author={Eugenia de la Torre and Melissa J. Mulla and Andrew G. Yu and Seung-Joon Lee and Paula B. Kavathas and Vikki M Abrahams},
  journal={Journal of immunology},
  volume={182 6},
It is well established that intrauterine infections can pose a threat to pregnancy by gaining access to the placenta and fetus, and clinical studies have strongly linked bacterial infections with preterm labor. Although Chlamydia trachomatis (Ct) can infect the placenta and decidua, little is known about its effects on trophoblast cell immune function. We have demonstrated that Ct infects trophoblast cells to form inclusions and completes the life cycle within these cells by generating… CONTINUE READING


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