Chlamydia trachomatis induces expression of IFN-gamma-inducible protein 10 and IFN-beta independent of TLR2 and TLR4, but largely dependent on MyD88.

Abstract

IFN-gamma-inducible protein 10 (IP-10) is a chemokine important in the attraction of T cells, which are essential for resolution of chlamydial genital tract infection. During infections with Gram-negative bacteria, the IP-10 response mediated through type I IFNs usually occurs as a result of TLR4 stimulation by bacterial LPS. However, we found that levels… (More)

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Cite this paper

@article{Nagarajan2005ChlamydiaTI, title={Chlamydia trachomatis induces expression of IFN-gamma-inducible protein 10 and IFN-beta independent of TLR2 and TLR4, but largely dependent on MyD88.}, author={Uma M. Nagarajan and David M. Ojcius and Lynn Stahl and Roger G. Rank and Toni L Darville}, journal={Journal of immunology}, year={2005}, volume={175 1}, pages={450-60} }