Chlamydia spp. development is differentially altered by treatment with the LpxC inhibitor LPC-011

@article{Cram2017ChlamydiaSD,
  title={Chlamydia spp. development is differentially altered by treatment with the LpxC inhibitor LPC-011},
  author={Erik D. Cram and D. Rockey and B. Dolan},
  journal={BMC Microbiology},
  year={2017},
  volume={17}
}
  • Erik D. Cram, D. Rockey, B. Dolan
  • Published 2017
  • Biology, Medicine
  • BMC Microbiology
  • BackgroundChlamydia species are obligate intracellular bacteria that infect a broad range of mammalian hosts. Members of related genera are pathogens of a variety of vertebrate and invertebrate species. Despite the diversity of Chlamydia, all species contain an outer membrane lipooligosaccharide (LOS) that is comprised of a genus-conserved, and genus-defining, trisaccharide 3-deoxy-D-manno-oct-2-ulosonic acid Kdo region. Recent studies with lipopolysaccharide inhibitors demonstrate that LOS is… CONTINUE READING
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